The "transfusion threshold" has dropped lower and lower over the years. We use to offer blood to anyone who was anemic and felt tired. Then we worried about AIDS and using a precious resource up too quickly.
I've seen hospitalized clients with severe anemia struggle to breathe, move and heal while well-meaning clinicians refuse to transfuse them until their hemoglobin fell below 7. (Normal hemoglobin is 12 or 13- 16 or 18, depending on sex).
A November 2024 study by Taccone, published in JAMA and presented at the 16th World Stroke Congress, demonstrates that giving a transfusion for hemoglobin less than 9 results in better neurologic outcomes compared to waiting for the hemoglobin to fall below 7 in people with acute brain injuries.
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