The gut microbiome has been tied to Parkinson's Disease. Now a study in Jama Neurology of 500,000 people followed for 15 years in the UK linked loneliness, yes loneliness, with Parkinson's Disease. This builds on what has already been established about the tie between loneliness and all-cause mortality, but still, I'm a bit amazed.
People who reported being lonely had a higher risk for PD (hazard ratio [HR] 1.37) — an association that remained after accounting for a wide variety of other medical and demographic factors. Loneliness was not associated with new PD in the first 5 years after baseline but was associated with PD risk in the subsequent 10 years of follow-up.
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